| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2021-05-16: CLE 109 at BKN 123 | May 16, 2021, noon | BKN | CLE | Barclays Center | Brooklyn | NY |
| NBA 2021-05-14: CLE 105 at WAS 120 | May 14, 2021, noon | WAS | CLE | Capital One Arena | Washington | DC |
| NBA 2021-05-12: BOS 94 at CLE 102 | May 12, 2021, 1 p.m. | CLE | BOS | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-05-10: IND 111 at CLE 102 | May 10, 2021, 12:30 p.m. | IND | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-05-09: DAL 124 at CLE 97 | May 9, 2021, noon | DAL | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-05-07: CLE 90 at DAL 110 | May 7, 2021, 1:30 p.m. | DAL | CLE | American Airlines Center | Dallas | TX |
| NBA 2021-05-05: POR 141 at CLE 105 | May 5, 2021, 12:30 p.m. | POR | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-05-04: PHX 134 at CLE 118 (OT) | May 4, 2021, noon | PHX | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-05-01: MIA 124 at CLE 107 | May 1, 2021, 1 p.m. | MIA | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-30: WAS 122 at CLE 93 | April 30, 2021, 12:30 p.m. | WAS | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-28: ORL 109 at CLE 104 | April 28, 2021, noon | ORL | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-26: CLE 96 at TOR 112 | April 26, 2021, 12:30 p.m. | TOR | CLE | Amalie Arena | Tampa | FL |
| NBA 2021-04-25: CLE 110 at WAS 119 | April 25, 2021, noon | WAS | CLE | Capital One Arena | Washington | DC |
| NBA 2021-04-23: CLE 102 at CHA 108 | April 23, 2021, 1 p.m. | CHA | CLE | Spectrum Center | Charlotte | NC |
| NBA 2021-04-21: CHI 105 at CLE 121 | April 21, 2021, noon | CLE | CHI | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-19: CLE 105 at DET 109 | April 19, 2021, noon | DET | CLE | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-17: CLE 96 at CHI 106 | April 17, 2021, 1 p.m. | CHI | CLE | United Center | Chicago | IL |
| NBA 2021-04-15: GSW 119 at CLE 101 | April 15, 2021, 1 p.m. | GSW | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-14: CLE 103 at CHA 90 | April 14, 2021, noon | CLE | CHA | Spectrum Center | Charlotte | NC |
| NBA 2021-04-11: NOP 116 at CLE 109 | April 11, 2021, noon | NOP | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-10: TOR 135 at CLE 115 | April 10, 2021, 12:30 p.m. | TOR | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-04-08: CLE 129 at OKC 102 | April 8, 2021, 1 p.m. | CLE | OKC | Chesapeake Energy Arena | Oklahoma City | OK |
| NBA 2021-04-05: CLE 125 at SAS 101 | April 5, 2021, noon | CLE | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-04-03: CLE 101 at MIA 115 | April 3, 2021, 1 p.m. | MIA | CLE | AmericanAirlines Arena | Miami | FL |
| NBA 2021-04-01: PHI 114 at CLE 94 | April 1, 2021, noon | PHI | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-03-29: CLE 75 at UTA 114 | March 29, 2021, 2 p.m. | UTA | CLE | Vivint Arena | Salt Lake City | UT |
| NBA 2021-03-27: CLE 98 at SAC 100 | March 27, 2021, 3 p.m. | SAC | CLE | Golden 1 Center | Sacramento | CA |
| NBA 2021-03-26: CLE 86 at LAL 100 | March 26, 2021, 3:30 p.m. | LAL | CLE | STAPLES Center | Los Angeles | CA |
| NBA 2021-03-24: CLE 103 at CHI 94 | March 24, 2021, 1 p.m. | CLE | CHI | United Center | Chicago | IL |
| NBA 2021-03-22: SAC 119 at CLE 105 | March 22, 2021, 12:30 p.m. | SAC | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-03-21: TOR 105 at CLE 116 | March 21, 2021, noon | CLE | TOR | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-03-19: SAS 116 at CLE 110 | March 19, 2021, 12:30 p.m. | SAS | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-03-17: BOS 110 at CLE 117 | March 17, 2021, 1 p.m. | CLE | BOS | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-03-16: CLE 98 at MIA 113 | March 16, 2021, 1 p.m. | MIA | CLE | AmericanAirlines Arena | Miami | FL |
| NBA 2021-03-14: CLE 82 at ATL 100 | March 14, 2021, 12:30 p.m. | ATL | CLE | State Farm Arena | Atlanta | GA |