| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2021-03-14: BOS 134 at HOU 107 | March 14, 2021, 1 p.m. | BOS | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-12: HOU 99 at UTA 114 | March 12, 2021, 3 p.m. | UTA | HOU | Vivint Arena | Salt Lake City | UT |
| NBA 2021-03-11: HOU 105 at SAC 125 | March 11, 2021, 3 p.m. | SAC | HOU | Golden 1 Center | Sacramento | CA |
| NBA 2021-03-03: BKN 132 at HOU 114 | March 3, 2021, 12:30 p.m. | BKN | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-01: CLE 101 at HOU 90 | March 1, 2021, 2 p.m. | CLE | HOU | Toyota Center | Houston | TX |
| NBA 2021-02-28: MEM 133 at HOU 84 | Feb. 28, 2021, 1 p.m. | MEM | HOU | Toyota Center | Houston | TX |
| NBA 2021-02-26: HOU 111 at TOR 122 | Feb. 26, 2021, 12:30 p.m. | TOR | HOU | Amalie Arena | Tampa | FL |
| NBA 2021-02-24: HOU 96 at CLE 112 | Feb. 24, 2021, 12:30 p.m. | CLE | HOU | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-02-22: CHI 120 at HOU 100 | Feb. 22, 2021, 1 p.m. | CHI | HOU | Toyota Center | Houston | TX |
| NBA 2021-02-17: HOU 113 at PHI 118 | Feb. 17, 2021, 12:30 p.m. | PHI | HOU | Wells Fargo Center | Philadelphia | PA |
| NBA 2021-02-15: HOU 119 at WAS 131 | Feb. 15, 2021, noon | WAS | HOU | Capital One Arena | Washington | DC |
| NBA 2021-02-13: HOU 99 at NYK 121 | Feb. 13, 2021, 1 p.m. | NYK | HOU | Madison Square Garden | New York | NY |
| NBA 2021-02-11: MIA 101 at HOU 94 | Feb. 11, 2021, 12:30 p.m. | MIA | HOU | Toyota Center | Houston | TX |
| NBA 2021-02-09: HOU 101 at NOP 130 | Feb. 9, 2021, 12:30 p.m. | NOP | HOU | Smoothie King Center | New Orleans | LA |
| NBA 2021-02-08: HOU 94 at CHA 119 | Feb. 8, 2021, noon | CHA | HOU | Spectrum Center | Charlotte | NC |
| NBA 2021-02-06: SAS 111 at HOU 106 | Feb. 6, 2021, 1 p.m. | SAS | HOU | Toyota Center | Houston | TX |
| NBA 2021-02-04: HOU 115 at MEM 103 | Feb. 4, 2021, 2 p.m. | HOU | MEM | FedExForum | Memphis | TN |
| NBA 2021-02-03: HOU 87 at OKC 104 | Feb. 3, 2021, 1 p.m. | OKC | HOU | Chesapeake Energy Arena | Oklahoma City | OK |
| NBA 2021-02-01: HOU 136 at OKC 106 | Feb. 1, 2021, 1 p.m. | HOU | OKC | Chesapeake Energy Arena | Oklahoma City | OK |
| NBA 2021-01-30: HOU 126 at NOP 112 | Jan. 30, 2021, 1 p.m. | HOU | NOP | Smoothie King Center | New Orleans | LA |
| NBA 2021-01-28: POR 101 at HOU 104 | Jan. 28, 2021, 12:30 p.m. | HOU | POR | Toyota Center | Houston | TX |
| NBA 2021-01-26: WAS 88 at HOU 107 | Jan. 26, 2021, 1 p.m. | HOU | WAS | Toyota Center | Houston | TX |
| NBA 2021-01-23: HOU 133 at DAL 108 | Jan. 23, 2021, 2 p.m. | HOU | DAL | American Airlines Center | Dallas | TX |
| NBA 2021-01-22: HOU 103 at DET 102 | Jan. 22, 2021, noon | HOU | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-01-20: PHX 109 at HOU 103 | Jan. 20, 2021, 2:30 p.m. | PHX | HOU | Toyota Center | Houston | TX |
| NBA 2021-01-18: HOU 120 at CHI 125 | Jan. 18, 2021, 1 p.m. | CHI | HOU | United Center | Chicago | IL |
| NBA 2021-01-16: HOU 91 at SAS 103 | Jan. 16, 2021, 10 a.m. | SAS | HOU | AT&T Center | San Antonio | TX |
| NBA 2021-01-14: HOU 109 at SAS 105 | Jan. 14, 2021, 12:30 p.m. | HOU | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-12: LAL 117 at HOU 100 | Jan. 12, 2021, 1 p.m. | LAL | HOU | Toyota Center | Houston | TX |
| NBA 2021-01-10: LAL 120 at HOU 102 | Jan. 10, 2021, noon | LAL | HOU | Toyota Center | Houston | TX |
| NBA 2021-01-08: ORL 90 at HOU 132 | Jan. 8, 2021, 1 p.m. | HOU | ORL | Toyota Center | Houston | TX |
| NBA 2021-01-06: HOU 107 at IND 114 | Jan. 6, 2021, noon | IND | HOU | Bankers Life Fieldhouse | Indianapolis | IN |
| NBA 2021-01-04: DAL 113 at HOU 100 | Jan. 4, 2021, 1 p.m. | DAL | HOU | Toyota Center | Houston | TX |
| NBA 2021-01-02: SAC 94 at HOU 102 | Jan. 2, 2021, 10 a.m. | HOU | SAC | Toyota Center | Houston | TX |
| NBA 2020-12-31: SAC 119 at HOU 122 | Dec. 31, 2020, noon | HOU | SAC | Toyota Center | Houston | TX |