| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2022-04-10: IND 126 at BKN 134 | April 10, 2022, 3:30 p.m. | BKN | IND | Barclays Center | Brooklyn | NY |
| NBA 2022-04-09: IND 120 at PHI 133 | April 9, 2022, 1 p.m. | PHI | IND | Wells Fargo Center | Philadelphia | PA |
| NBA 2022-04-05: PHI 131 at IND 122 | April 5, 2022, 7 p.m. | PHI | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-04-03: DET 121 at IND 117 | April 3, 2022, 5 p.m. | DET | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-04-01: IND 123 at BOS 128 | April 1, 2022, 7:30 p.m. | BOS | IND | TD Garden | Boston | MA |
| NBA 2022-03-30: DEN 125 at IND 118 | March 30, 2022, 7 p.m. | DEN | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-28: ATL 132 at IND 123 | March 28, 2022, 7 p.m. | ATL | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-26: IND 91 at TOR 131 | March 26, 2022, 7:30 p.m. | TOR | IND | Scotiabank Arena | Toronto | ON |
| NBA 2022-03-24: IND 103 at MEM 133 | March 24, 2022, 8 p.m. | MEM | IND | FedExForum | Memphis | TN |
| NBA 2022-03-23: SAC 110 at IND 109 | March 23, 2022, 7 p.m. | SAC | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-20: POR 98 at IND 129 | March 20, 2022, 3:30 p.m. | IND | POR | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-18: IND 121 at HOU 118 | March 18, 2022, 8 p.m. | IND | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-15: MEM 135 at IND 102 | March 15, 2022, 7 p.m. | MEM | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-13: IND 128 at ATL 131 | March 13, 2022, 7 p.m. | ATL | IND | State Farm Arena | Atlanta | GA |
| NBA 2022-03-12: IND 119 at SAS 108 | March 12, 2022, 8 p.m. | IND | SAS | AT&T Center | San Antonio | TX |
| NBA 2022-03-08: CLE 127 at IND 124 | March 8, 2022, 7 p.m. | CLE | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-06: IND 123 at WAS 133 | March 6, 2022, 6 p.m. | WAS | IND | Capital One Arena | Washington | DC |
| NBA 2022-03-04: IND 106 at DET 111 | March 4, 2022, 7 p.m. | DET | IND | Little Caesars Arena | Detroit | MI |
| NBA 2022-03-02: IND 122 at ORL 114 (OT) | March 2, 2022, 7 p.m. | IND | ORL | Amway Center | Orlando | FL |
| NBA 2022-02-28: IND 103 at ORL 119 | Feb. 28, 2022, 7 p.m. | ORL | IND | Amway Center | Orlando | FL |
| NBA 2022-02-27: BOS 107 at IND 128 | Feb. 27, 2022, 5 p.m. | IND | BOS | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-25: OKC 129 at IND 125 (OT) | Feb. 25, 2022, 7 p.m. | OKC | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-16: WAS 108 at IND 113 | Feb. 16, 2022, 7:30 p.m. | IND | WAS | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-15: IND 119 at MIL 128 | Feb. 15, 2022, 8 p.m. | MIL | IND | Fiserv Forum | Milwaukee | WI |
| NBA 2022-02-13: MIN 129 at IND 120 | Feb. 13, 2022, 3 p.m. | MIN | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-11: CLE 120 at IND 113 | Feb. 11, 2022, 7 p.m. | CLE | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-08: IND 112 at ATL 133 | Feb. 8, 2022, 7:30 p.m. | ATL | IND | State Farm Arena | Atlanta | GA |
| NBA 2022-02-06: IND 85 at CLE 98 | Feb. 6, 2022, 6 p.m. | CLE | IND | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-02-04: CHI 122 at IND 115 | Feb. 4, 2022, 7 p.m. | CHI | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-02: ORL 119 at IND 118 | Feb. 2, 2022, 7 p.m. | ORL | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-01-31: LAC 116 at IND 122 | Jan. 31, 2022, 7 p.m. | IND | LAC | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-01-29: IND 105 at DAL 132 | Jan. 29, 2022, 7 p.m. | DAL | IND | American Airlines Center | Dallas | TX |
| NBA 2022-01-28: IND 113 at OKC 110 (OT) | Jan. 28, 2022, 8 p.m. | IND | OKC | Paycom Center | Oklahoma City | OK |
| NBA 2022-01-26: CHA 158 at IND 126 | Jan. 26, 2022, 7 p.m. | CHA | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-01-24: IND 113 at NOP 117 | Jan. 24, 2022, 8 p.m. | NOP | IND | Smoothie King Center | New Orleans | LA |