| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2022-04-10: ATL 130 at HOU 114 | April 10, 2022, 3:30 p.m. | ATL | HOU | Toyota Center | Houston | TX |
| NBA 2022-04-08: HOU 115 at TOR 117 | April 8, 2022, 7:30 p.m. | TOR | HOU | Scotiabank Arena | Toronto | ON |
| NBA 2022-04-05: HOU 105 at BKN 118 | April 5, 2022, 7:30 p.m. | BKN | HOU | Barclays Center | Brooklyn | NY |
| NBA 2022-04-03: MIN 139 at HOU 132 | April 3, 2022, 7 p.m. | MIN | HOU | Toyota Center | Houston | TX |
| NBA 2022-04-01: SAC 122 at HOU 117 | April 1, 2022, 8 p.m. | SAC | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-30: SAC 121 at HOU 118 | March 30, 2022, 8 p.m. | SAC | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-28: SAS 123 at HOU 120 | March 28, 2022, 8 p.m. | SAS | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-26: HOU 115 at POR 98 | March 26, 2022, 10 p.m. | HOU | POR | Moda Center | Portland | OR |
| NBA 2022-03-25: HOU 125 at POR 106 | March 25, 2022, 10 p.m. | HOU | POR | Moda Center | Portland | OR |
| NBA 2022-03-23: HOU 91 at DAL 110 | March 23, 2022, 8:30 p.m. | DAL | HOU | American Airlines Center | Dallas | TX |
| NBA 2022-03-21: WAS 97 at HOU 115 | March 21, 2022, 8 p.m. | HOU | WAS | Toyota Center | Houston | TX |
| NBA 2022-03-20: MEM 122 at HOU 98 | March 20, 2022, 3:30 p.m. | MEM | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-18: IND 121 at HOU 118 | March 18, 2022, 8 p.m. | IND | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-16: PHX 129 at HOU 112 | March 16, 2022, 8 p.m. | PHX | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-13: HOU 105 at NOP 130 | March 13, 2022, 7 p.m. | NOP | HOU | Smoothie King Center | New Orleans | LA |
| NBA 2022-03-11: DAL 113 at HOU 100 | March 11, 2022, 8 p.m. | DAL | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-09: LAL 130 at HOU 139 (OT) | March 9, 2022, 8 p.m. | HOU | LAL | Toyota Center | Houston | TX |
| NBA 2022-03-07: HOU 106 at MIA 123 | March 7, 2022, 7:30 p.m. | MIA | HOU | FTX Arena | Miami | FL |
| NBA 2022-03-06: MEM 112 at HOU 123 | March 6, 2022, 7 p.m. | HOU | MEM | Toyota Center | Houston | TX |
| NBA 2022-03-04: HOU 101 at DEN 116 | March 4, 2022, 9 p.m. | DEN | HOU | Ball Arena | Denver | CO |
| NBA 2022-03-02: UTA 132 at HOU 127 (OT) | March 2, 2022, 8 p.m. | UTA | HOU | Toyota Center | Houston | TX |
| NBA 2022-03-01: LAC 113 at HOU 100 | March 1, 2022, 8 p.m. | LAC | HOU | Toyota Center | Houston | TX |
| NBA 2022-02-27: LAC 99 at HOU 98 | Feb. 27, 2022, 7 p.m. | LAC | HOU | Toyota Center | Houston | TX |
| NBA 2022-02-25: HOU 111 at ORL 119 | Feb. 25, 2022, 7 p.m. | ORL | HOU | Amway Center | Orlando | FL |
| NBA 2022-02-17: HOU 111 at LAC 142 | Feb. 17, 2022, 10:30 p.m. | LAC | HOU | Crypto.com Arena | Los Angeles | CA |
| NBA 2022-02-16: HOU 121 at PHX 124 | Feb. 16, 2022, 9 p.m. | PHX | HOU | Footprint Center | Phoenix | AZ |
| NBA 2022-02-14: HOU 101 at UTA 135 | Feb. 14, 2022, 9 p.m. | UTA | HOU | Vivint Arena | Salt Lake City | UT |
| NBA 2022-02-10: TOR 139 at HOU 120 | Feb. 10, 2022, 8 p.m. | TOR | HOU | Toyota Center | Houston | TX |
| NBA 2022-02-08: HOU 97 at NOP 110 | Feb. 8, 2022, 8 p.m. | NOP | HOU | Smoothie King Center | New Orleans | LA |
| NBA 2022-02-06: NOP 120 at HOU 107 | Feb. 6, 2022, 7 p.m. | NOP | HOU | Toyota Center | Houston | TX |
| NBA 2022-02-04: HOU 106 at SAS 131 | Feb. 4, 2022, 8:30 p.m. | SAS | HOU | AT&T Center | San Antonio | TX |
| NBA 2022-02-02: CLE 104 at HOU 115 | Feb. 2, 2022, 8 p.m. | HOU | CLE | Toyota Center | Houston | TX |
| NBA 2022-01-31: GSW 122 at HOU 108 | Jan. 31, 2022, 8 p.m. | GSW | HOU | Toyota Center | Houston | TX |
| NBA 2022-01-28: POR 125 at HOU 110 | Jan. 28, 2022, 8 p.m. | POR | HOU | Toyota Center | Houston | TX |
| NBA 2022-01-25: SAS 134 at HOU 104 | Jan. 25, 2022, 8 p.m. | SAS | HOU | Toyota Center | Houston | TX |