| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2022-04-10: MIL 115 at CLE 133 | April 10, 2022, 3:30 p.m. | CLE | MIL | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-04-08: CLE 107 at BKN 118 | April 8, 2022, 7:30 p.m. | BKN | CLE | Barclays Center | Brooklyn | NY |
| NBA 2022-04-05: CLE 115 at ORL 120 | April 5, 2022, 7 p.m. | ORL | CLE | Amway Center | Orlando | FL |
| NBA 2022-04-03: PHI 112 at CLE 108 | April 3, 2022, 6 p.m. | PHI | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-04-02: CLE 119 at NYK 101 | April 2, 2022, 1 p.m. | CLE | NYK | Madison Square Garden | New York | NY |
| NBA 2022-03-31: CLE 107 at ATL 131 | March 31, 2022, 7:30 p.m. | ATL | CLE | State Farm Arena | Atlanta | GA |
| NBA 2022-03-30: DAL 120 at CLE 112 | March 30, 2022, 7 p.m. | DAL | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-28: ORL 101 at CLE 107 | March 28, 2022, 7 p.m. | CLE | ORL | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-26: CHI 98 at CLE 94 | March 26, 2022, 8 p.m. | CHI | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-24: CLE 104 at TOR 117 | March 24, 2022, 7:30 p.m. | TOR | CLE | Scotiabank Arena | Toronto | ON |
| NBA 2022-03-21: LAL 131 at CLE 120 | March 21, 2022, 7 p.m. | LAL | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-19: DET 109 at CLE 113 | March 19, 2022, 8 p.m. | CLE | DET | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-18: DEN 116 at CLE 119 (OT) | March 18, 2022, 7:30 p.m. | CLE | DEN | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-16: PHI 118 at CLE 114 | March 16, 2022, 7 p.m. | PHI | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-14: LAC 111 at CLE 120 (OT) | March 14, 2022, 7 p.m. | CLE | LAC | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-12: CLE 91 at CHI 101 | March 12, 2022, 8 p.m. | CHI | CLE | United Center | Chicago | IL |
| NBA 2022-03-11: CLE 105 at MIA 117 | March 11, 2022, 8 p.m. | MIA | CLE | FTX Arena | Miami | FL |
| NBA 2022-03-08: CLE 127 at IND 124 | March 8, 2022, 7 p.m. | CLE | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-03-06: TOR 96 at CLE 104 | March 6, 2022, 7:30 p.m. | CLE | TOR | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-03-04: CLE 119 at PHI 125 | March 4, 2022, 7 p.m. | PHI | CLE | Wells Fargo Center | Philadelphia | PA |
| NBA 2022-03-02: CHA 119 at CLE 98 | March 2, 2022, 7 p.m. | CHA | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-02-28: MIN 127 at CLE 122 | Feb. 28, 2022, 7 p.m. | MIN | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-02-26: WAS 86 at CLE 92 | Feb. 26, 2022, 8 p.m. | CLE | WAS | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-02-24: CLE 103 at DET 106 | Feb. 24, 2022, 7 p.m. | DET | CLE | Little Caesars Arena | Detroit | MI |
| NBA 2022-02-15: CLE 116 at ATL 124 | Feb. 15, 2022, 7:30 p.m. | ATL | CLE | State Farm Arena | Atlanta | GA |
| NBA 2022-02-12: CLE 93 at PHI 103 | Feb. 12, 2022, 7:30 p.m. | PHI | CLE | Wells Fargo Center | Philadelphia | PA |
| NBA 2022-02-11: CLE 120 at IND 113 | Feb. 11, 2022, 7 p.m. | CLE | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2022-02-09: SAS 92 at CLE 105 | Feb. 9, 2022, 7 p.m. | CLE | SAS | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-02-06: IND 85 at CLE 98 | Feb. 6, 2022, 6 p.m. | CLE | IND | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-02-04: CLE 102 at CHA 101 | Feb. 4, 2022, 7 p.m. | CLE | CHA | Spectrum Center | Charlotte | NC |
| NBA 2022-02-02: CLE 104 at HOU 115 | Feb. 2, 2022, 8 p.m. | HOU | CLE | Toyota Center | Houston | TX |
| NBA 2022-01-31: NOP 90 at CLE 93 | Jan. 31, 2022, 7 p.m. | CLE | NOP | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-01-30: CLE 105 at DET 115 | Jan. 30, 2022, 6 p.m. | DET | CLE | Little Caesars Arena | Detroit | MI |
| NBA 2022-01-26: MIL 99 at CLE 115 | Jan. 26, 2022, 7 p.m. | CLE | MIL | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2022-01-24: NYK 93 at CLE 95 | Jan. 24, 2022, 7 p.m. | CLE | NYK | Rocket Mortgage FieldHouse | Cleveland | OH |