| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2021-10-15: CLE 110 at IND 94 | Oct. 15, 2021, noon | CLE | IND | Gainbridge Fieldhouse | Indianapolis | IN |
| NBA 2021-10-10: CHI 102 at CLE 101 | Oct. 10, 2021, noon | CHI | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-10-08: IND 109 at CLE 100 | Oct. 8, 2021, noon | IND | CLE | Rocket Mortgage FieldHouse | Cleveland | OH |
| NBA 2021-10-06: CLE 99 at ATL 96 | Oct. 6, 2021, 12:30 p.m. | CLE | ATL | State Farm Arena | Atlanta | GA |
| NBA 2021-10-05: CLE 95 at CHI 131 | Oct. 5, 2021, 1 p.m. | CHI | CLE | United Center | Chicago | IL |