| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2021-05-16: HOU 95 at ATL 124 | May 16, 2021, noon | ATL | HOU | State Farm Arena | Atlanta | GA |
| NBA 2021-05-14: LAC 115 at HOU 122 | May 14, 2021, 2 p.m. | HOU | LAC | Toyota Center | Houston | TX |
| NBA 2021-05-12: HOU 122 at LAL 124 | May 12, 2021, 3:30 p.m. | LAL | HOU | STAPLES Center | Los Angeles | CA |
| NBA 2021-05-10: HOU 129 at POR 140 | May 10, 2021, 3 p.m. | POR | HOU | Moda Center | Portland | OR |
| NBA 2021-05-08: HOU 116 at UTA 124 | May 8, 2021, 3 p.m. | UTA | HOU | Vivint Arena | Salt Lake City | UT |
| NBA 2021-05-07: HOU 133 at MIL 141 | May 7, 2021, 1 p.m. | MIL | HOU | Fiserv Forum | Milwaukee | WI |
| NBA 2021-05-05: PHI 135 at HOU 115 | May 5, 2021, 1 p.m. | PHI | HOU | Toyota Center | Houston | TX |
| NBA 2021-05-02: NYK 122 at HOU 97 | May 2, 2021, 1 p.m. | NYK | HOU | Toyota Center | Houston | TX |
| NBA 2021-05-01: GSW 113 at HOU 87 | May 1, 2021, 12:30 p.m. | GSW | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-29: MIL 136 at HOU 143 | April 29, 2021, 1 p.m. | HOU | MIL | Toyota Center | Houston | TX |
| NBA 2021-04-27: MIN 114 at HOU 107 | April 27, 2021, 2 p.m. | MIN | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-24: HOU 116 at DEN 129 | April 24, 2021, 3 p.m. | DEN | HOU | Ball Arena | Denver | CO |
| NBA 2021-04-23: LAC 109 at HOU 104 | April 23, 2021, 1 p.m. | LAC | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-21: UTA 112 at HOU 89 | April 21, 2021, 1 p.m. | UTA | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-19: HOU 91 at MIA 113 | April 19, 2021, 1 p.m. | MIA | HOU | AmericanAirlines Arena | Miami | FL |
| NBA 2021-04-18: HOU 114 at ORL 110 | April 18, 2021, noon | HOU | ORL | Amway Center | Orlando | FL |
| NBA 2021-04-16: DEN 128 at HOU 99 | April 16, 2021, 1 p.m. | DEN | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-14: IND 132 at HOU 124 | April 14, 2021, 2 p.m. | IND | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-12: HOU 120 at PHX 126 | April 12, 2021, 3 p.m. | PHX | HOU | Phoenix Suns Arena | Phoenix | AZ |
| NBA 2021-04-10: HOU 109 at GSW 125 | April 10, 2021, 3 p.m. | GSW | HOU | Chase Center | San Francisco | CA |
| NBA 2021-04-09: HOU 109 at LAC 126 | April 9, 2021, 3 p.m. | LAC | HOU | STAPLES Center | Los Angeles | CA |
| NBA 2021-04-07: DAL 93 at HOU 102 | April 7, 2021, 1 p.m. | HOU | DAL | Toyota Center | Houston | TX |
| NBA 2021-04-05: PHX 133 at HOU 130 | April 5, 2021, 1 p.m. | PHX | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-04: NOP 122 at HOU 115 | April 4, 2021, 1 p.m. | NOP | HOU | Toyota Center | Houston | TX |
| NBA 2021-04-02: HOU 102 at BOS 118 | April 2, 2021, 12:30 p.m. | BOS | HOU | TD Garden | Boston | MA |
| NBA 2021-03-31: HOU 108 at BKN 120 | March 31, 2021, 12:30 p.m. | BKN | HOU | Barclays Center | Brooklyn | NY |
| NBA 2021-03-29: MEM 120 at HOU 110 | March 29, 2021, 1 p.m. | MEM | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-27: HOU 129 at MIN 107 | March 27, 2021, 1 p.m. | HOU | MIN | Target Center | Minneapolis | MN |
| NBA 2021-03-26: HOU 101 at MIN 107 | March 26, 2021, 1 p.m. | MIN | HOU | Target Center | Minneapolis | MN |
| NBA 2021-03-24: CHA 122 at HOU 97 | March 24, 2021, 1 p.m. | CHA | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-22: TOR 99 at HOU 117 | March 22, 2021, 2 p.m. | HOU | TOR | Toyota Center | Houston | TX |
| NBA 2021-03-21: OKC 114 at HOU 112 | March 21, 2021, 7 a.m. | OKC | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-19: DET 113 at HOU 100 | March 19, 2021, 1 p.m. | DET | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-17: GSW 108 at HOU 94 | March 17, 2021, 1 p.m. | GSW | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-16: ATL 119 at HOU 107 | March 16, 2021, 1 p.m. | ATL | HOU | Toyota Center | Houston | TX |