| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2021-05-16: MIA 120 at DET 107 | May 16, 2021, 1 p.m. | MIA | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-14: DEN 104 at DET 91 | May 14, 2021, 1 p.m. | DEN | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-11: MIN 119 at DET 100 | May 11, 2021, noon | MIN | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-09: CHI 108 at DET 96 | May 9, 2021, 1 p.m. | CHI | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-08: DET 104 at PHI 118 | May 8, 2021, noon | PHI | DET | Wells Fargo Center | Philadelphia | PA |
| NBA 2021-05-06: MEM 97 at DET 111 | May 6, 2021, 1 p.m. | DET | MEM | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-04: CHA 102 at DET 99 | May 4, 2021, noon | CHA | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-03: ORL 119 at DET 112 | May 3, 2021, noon | ORL | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-05-01: DET 94 at CHA 107 | May 1, 2021, noon | CHA | DET | Spectrum Center | Charlotte | NC |
| NBA 2021-04-29: DAL 115 at DET 105 | April 29, 2021, noon | DAL | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-26: ATL 86 at DET 100 | April 26, 2021, noon | DET | ATL | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-24: DET 109 at IND 115 | April 24, 2021, noon | IND | DET | Bankers Life Fieldhouse | Indianapolis | IN |
| NBA 2021-04-22: DET 91 at SAS 106 | April 22, 2021, 1:30 p.m. | SAS | DET | AT&T Center | San Antonio | TX |
| NBA 2021-04-21: DET 117 at DAL 127 | April 21, 2021, 1:30 p.m. | DAL | DET | American Airlines Center | Dallas | TX |
| NBA 2021-04-19: CLE 105 at DET 109 | April 19, 2021, noon | DET | CLE | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-17: DET 100 at WAS 121 | April 17, 2021, 1 p.m. | WAS | DET | Capital One Arena | Washington | DC |
| NBA 2021-04-16: OKC 104 at DET 110 | April 16, 2021, noon | DET | OKC | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-14: LAC 100 at DET 98 | April 14, 2021, 1 p.m. | LAC | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-11: DET 124 at LAC 131 | April 11, 2021, 3 p.m. | LAC | DET | STAPLES Center | Los Angeles | CA |
| NBA 2021-04-10: DET 103 at POR 118 | April 10, 2021, 3 p.m. | POR | DET | Moda Center | Portland | OR |
| NBA 2021-04-08: DET 113 at SAC 101 | April 8, 2021, 3 p.m. | DET | SAC | Golden 1 Center | Sacramento | CA |
| NBA 2021-04-06: DET 119 at DEN 134 | April 6, 2021, 2 p.m. | DEN | DET | Ball Arena | Denver | CO |
| NBA 2021-04-05: DET 132 at OKC 108 | April 5, 2021, noon | DET | OKC | Chesapeake Energy Arena | Oklahoma City | OK |
| NBA 2021-04-03: NYK 125 at DET 81 | April 3, 2021, 1 p.m. | NYK | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-04-01: WAS 91 at DET 120 | April 1, 2021, noon | DET | WAS | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-31: POR 124 at DET 101 | March 31, 2021, noon | POR | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-29: TOR 104 at DET 118 | March 29, 2021, 1 p.m. | DET | TOR | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-27: DET 92 at WAS 106 | March 27, 2021, 1 p.m. | WAS | DET | Capital One Arena | Washington | DC |
| NBA 2021-03-26: BKN 113 at DET 111 | March 26, 2021, noon | BKN | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-24: DET 111 at IND 116 | March 24, 2021, noon | IND | DET | Bankers Life Fieldhouse | Indianapolis | IN |
| NBA 2021-03-21: CHI 100 at DET 86 | March 21, 2021, noon | CHI | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-19: DET 113 at HOU 100 | March 19, 2021, 1 p.m. | DET | HOU | Toyota Center | Houston | TX |
| NBA 2021-03-17: TOR 112 at DET 116 | March 17, 2021, noon | DET | TOR | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-15: SAS 109 at DET 99 | March 15, 2021, 1 p.m. | SAS | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-13: DET 95 at BKN 100 | March 13, 2021, noon | BKN | DET | Barclays Center | Brooklyn | NY |