| Game | Time (ET) | Winning Team | Losing Team | Arena | City | State |
|---|---|---|---|---|---|---|
| NBA 2021-03-17: SAS 106 at CHI 99 | March 17, 2021, 1 p.m. | SAS | CHI | United Center | Chicago | IL |
| NBA 2021-03-15: SAS 109 at DET 99 | March 15, 2021, 1 p.m. | SAS | DET | Little Caesars Arena | Detroit | MI |
| NBA 2021-03-14: SAS 99 at PHI 134 | March 14, 2021, 11:30 a.m. | PHI | SAS | Wells Fargo Center | Philadelphia | PA |
| NBA 2021-03-12: ORL 77 at SAS 104 | March 12, 2021, 2 p.m. | SAS | ORL | AT&T Center | San Antonio | TX |
| NBA 2021-03-10: SAS 104 at DAL 115 | March 10, 2021, 1:30 p.m. | DAL | SAS | American Airlines Center | Dallas | TX |
| NBA 2021-03-04: OKC 107 at SAS 102 | March 4, 2021, 2 p.m. | OKC | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-03-02: NYK 93 at SAS 119 | March 2, 2021, 1:30 p.m. | SAS | NYK | AT&T Center | San Antonio | TX |
| NBA 2021-03-01: BKN 124 at SAS 113 (OT) | March 1, 2021, 1:30 p.m. | BKN | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-02-27: NOP 114 at SAS 117 | Feb. 27, 2021, 1 p.m. | SAS | NOP | AT&T Center | San Antonio | TX |
| NBA 2021-02-24: SAS 99 at OKC 102 | Feb. 24, 2021, 1 p.m. | OKC | SAS | Chesapeake Energy Arena | Oklahoma City | OK |
| NBA 2021-02-14: SAS 122 at CHA 110 | Feb. 14, 2021, noon | SAS | CHA | Spectrum Center | Charlotte | NC |
| NBA 2021-02-12: SAS 125 at ATL 114 | Feb. 12, 2021, 12:30 p.m. | SAS | ATL | State Farm Arena | Atlanta | GA |
| NBA 2021-02-09: GSW 114 at SAS 91 | Feb. 9, 2021, 1:30 p.m. | GSW | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-02-08: GSW 100 at SAS 105 | Feb. 8, 2021, 1:30 p.m. | SAS | GSW | AT&T Center | San Antonio | TX |
| NBA 2021-02-06: SAS 111 at HOU 106 | Feb. 6, 2021, 1 p.m. | SAS | HOU | Toyota Center | Houston | TX |
| NBA 2021-02-03: MIN 108 at SAS 111 | Feb. 3, 2021, 1:30 p.m. | SAS | MIN | AT&T Center | San Antonio | TX |
| NBA 2021-02-01: MEM 133 at SAS 102 | Feb. 1, 2021, 1:30 p.m. | MEM | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-30: MEM 129 at SAS 112 | Jan. 30, 2021, 1:30 p.m. | MEM | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-29: DEN 109 at SAS 119 | Jan. 29, 2021, 1:30 p.m. | SAS | DEN | AT&T Center | San Antonio | TX |
| NBA 2021-01-27: BOS 106 at SAS 110 | Jan. 27, 2021, 1:30 p.m. | SAS | BOS | AT&T Center | San Antonio | TX |
| NBA 2021-01-24: WAS 101 at SAS 121 | Jan. 24, 2021, 1 p.m. | SAS | WAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-22: DAL 122 at SAS 117 | Jan. 22, 2021, 1:30 p.m. | DAL | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-20: SAS 99 at GSW 121 | Jan. 20, 2021, 3 p.m. | GSW | SAS | Chase Center | San Francisco | CA |
| NBA 2021-01-18: SAS 125 at POR 104 | Jan. 18, 2021, 8 a.m. | SAS | POR | Moda Center | Portland | OR |
| NBA 2021-01-16: HOU 91 at SAS 103 | Jan. 16, 2021, 10 a.m. | SAS | HOU | AT&T Center | San Antonio | TX |
| NBA 2021-01-14: HOU 109 at SAS 105 | Jan. 14, 2021, 12:30 p.m. | HOU | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-12: SAS 112 at OKC 102 | Jan. 12, 2021, 1 p.m. | SAS | OKC | Chesapeake Energy Arena | Oklahoma City | OK |
| NBA 2021-01-10: SAS 88 at MIN 96 | Jan. 10, 2021, 1 p.m. | MIN | SAS | Target Center | Minneapolis | MN |
| NBA 2021-01-09: SAS 125 at MIN 122 (OT) | Jan. 9, 2021, 1 p.m. | SAS | MIN | Target Center | Minneapolis | MN |
| NBA 2021-01-07: SAS 118 at LAL 109 | Jan. 7, 2021, 3 p.m. | SAS | LAL | STAPLES Center | Los Angeles | CA |
| NBA 2021-01-05: SAS 116 at LAC 113 | Jan. 5, 2021, 3 p.m. | SAS | LAC | STAPLES Center | Los Angeles | CA |
| NBA 2021-01-03: UTA 130 at SAS 109 | Jan. 3, 2021, noon | UTA | SAS | AT&T Center | San Antonio | TX |
| NBA 2021-01-01: LAL 109 at SAS 103 | Jan. 1, 2021, 1 p.m. | LAL | SAS | AT&T Center | San Antonio | TX |
| NBA 2020-12-30: LAL 121 at SAS 107 | Dec. 30, 2020, 1:30 p.m. | LAL | SAS | AT&T Center | San Antonio | TX |
| NBA 2020-12-27: SAS 95 at NOP 98 | Dec. 27, 2020, noon | NOP | SAS | Smoothie King Center | New Orleans | LA |