| Game | Q1 | Q2 | Q3 | Q4 | OT | +/- Q1 | +/- Q2 | +/- Q3 | +/- Q4 | +/- OT | LL | PP | 2CP | FBP | OTP |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NBA 2022-04-10: SAS 120 at DAL 130 | 29 | 30 | 23 | 38 | 0 | 1 | -1 | -15 | 5 | 0 | 4 | 52 | 10 | 19 | 18 |
| NBA 2022-04-09: GSW 100 at SAS 94 | 21 | 23 | 27 | 23 | 0 | -2 | -8 | 3 | 1 | 0 | 6 | 34 | 7 | 11 | 7 |
| NBA 2022-04-07: SAS 121 at MIN 127 | 35 | 22 | 25 | 39 | 0 | 5 | -12 | -8 | 9 | 0 | 5 | 58 | 13 | 18 | 18 |
| NBA 2022-04-05: SAS 116 at DEN 97 | 32 | 32 | 21 | 31 | 0 | 2 | 18 | -14 | 13 | 0 | 21 | 54 | 9 | 13 | 12 |
| NBA 2022-04-03: POR 92 at SAS 113 | 26 | 22 | 34 | 31 | 0 | 3 | -11 | 18 | 11 | 0 | 21 | 42 | 25 | 13 | 16 |
| NBA 2022-04-01: POR 111 at SAS 130 | 34 | 43 | 24 | 29 | 0 | 5 | 23 | -8 | -1 | 0 | 31 | 52 | 9 | 15 | 24 |
| NBA 2022-03-30: MEM 112 at SAS 111 | 27 | 25 | 34 | 25 | 0 | -4 | -9 | 6 | 6 | 0 | 0 | 48 | 14 | 13 | 18 |
| NBA 2022-03-28: SAS 123 at HOU 120 | 39 | 28 | 29 | 27 | 0 | 8 | 4 | 0 | -9 | 0 | 16 | 72 | 28 | 20 | 12 |
| NBA 2022-03-26: SAS 107 at NOP 103 | 22 | 36 | 26 | 23 | 0 | -10 | 11 | -1 | 4 | 0 | 10 | 54 | 22 | 2 | 7 |
| NBA 2022-03-23: SAS 133 at POR 96 | 45 | 36 | 33 | 19 | 0 | 18 | 10 | 5 | 4 | 0 | 43 | 48 | 18 | 25 | 14 |
| NBA 2022-03-20: SAS 110 at GSW 108 | 36 | 27 | 20 | 27 | 0 | 14 | -8 | -7 | 3 | 0 | 14 | 34 | 16 | 8 | 14 |
| NBA 2022-03-18: NOP 124 at SAS 91 | 10 | 23 | 24 | 34 | 0 | -25 | -6 | -7 | 5 | 0 | 0 | 32 | 15 | 8 | 22 |
| NBA 2022-03-16: OKC 120 at SAS 122 | 37 | 31 | 30 | 24 | 0 | 8 | 4 | -5 | -5 | 0 | 16 | 44 | 24 | 2 | 22 |
| NBA 2022-03-14: MIN 149 at SAS 139 | 32 | 41 | 33 | 33 | 0 | -8 | 6 | -13 | 5 | 0 | 1 | 64 | 13 | 21 | 18 |
| NBA 2022-03-12: IND 119 at SAS 108 | 26 | 38 | 18 | 26 | 0 | -8 | 1 | -8 | 4 | 0 | 6 | 52 | 15 | 14 | 17 |
| NBA 2022-03-11: UTA 102 at SAS 104 | 30 | 20 | 14 | 40 | 0 | -3 | -6 | -1 | 12 | 0 | 4 | 42 | 13 | 7 | 15 |
| NBA 2022-03-09: TOR 119 at SAS 104 | 29 | 32 | 23 | 20 | 0 | -5 | 8 | -10 | -8 | 0 | 7 | 46 | 8 | 9 | 23 |
| NBA 2022-03-07: LAL 110 at SAS 117 | 31 | 31 | 33 | 22 | 0 | 9 | -3 | -3 | 4 | 0 | 14 | 64 | 11 | 18 | 27 |
| NBA 2022-03-05: SAS 117 at CHA 123 | 30 | 30 | 37 | 20 | 0 | -1 | -1 | 0 | -4 | 0 | 6 | 56 | 15 | 18 | 17 |
| NBA 2022-03-03: SAC 115 at SAS 112 | 27 | 24 | 31 | 30 | 0 | -3 | -10 | 7 | 3 | 0 | 4 | 64 | 12 | 13 | 17 |
| NBA 2022-02-28: SAS 105 at MEM 118 | 34 | 24 | 27 | 20 | 0 | -8 | -2 | -1 | -2 | 0 | 6 | 46 | 9 | 15 | 11 |
| NBA 2022-02-26: SAS 129 at MIA 133 | 40 | 18 | 39 | 32 | 0 | 12 | -15 | 1 | -2 | 0 | 16 | 62 | 19 | 21 | 31 |
| NBA 2022-02-25: SAS 157 at WAS 153 (OT) | 30 | 45 | 26 | 29 | 27 | -3 | 7 | -3 | -1 | 4 | 11 | 74 | 27 | 9 | 19 |
| NBA 2022-02-16: SAS 114 at OKC 106 | 34 | 39 | 16 | 25 | 0 | 5 | 10 | -7 | 0 | 0 | 16 | 60 | 15 | 9 | 10 |
| NBA 2022-02-14: SAS 109 at CHI 120 | 27 | 30 | 32 | 20 | 0 | -2 | 0 | 8 | -17 | 0 | 7 | 70 | 6 | 11 | 8 |
| NBA 2022-02-12: SAS 124 at NOP 114 | 37 | 22 | 39 | 26 | 0 | 4 | 2 | 10 | -6 | 0 | 18 | 50 | 9 | 13 | 4 |
| NBA 2022-02-11: SAS 136 at ATL 121 | 43 | 30 | 30 | 33 | 0 | 14 | 3 | -1 | -1 | 0 | 26 | 48 | 13 | 23 | 25 |
| NBA 2022-02-09: SAS 92 at CLE 105 | 30 | 18 | 25 | 19 | 0 | 1 | -10 | -2 | -2 | 0 | 8 | 54 | 10 | 18 | 17 |
| NBA 2022-02-04: HOU 106 at SAS 131 | 33 | 24 | 40 | 34 | 0 | 8 | -5 | 17 | 5 | 0 | 28 | 68 | 19 | 24 | 18 |
| NBA 2022-02-03: MIA 112 at SAS 95 | 19 | 28 | 19 | 29 | 0 | -2 | -8 | -12 | 5 | 0 | 6 | 36 | 9 | 7 | 23 |
| NBA 2022-02-01: GSW 124 at SAS 120 | 36 | 33 | 35 | 16 | 0 | 6 | 2 | 7 | -19 | 0 | 17 | 54 | 5 | 17 | 19 |
| NBA 2022-01-30: SAS 110 at PHX 115 | 31 | 24 | 36 | 19 | 0 | 8 | -3 | 7 | -17 | 0 | 12 | 44 | 8 | 6 | 14 |
| NBA 2022-01-28: CHI 122 at SAS 131 | 29 | 34 | 35 | 33 | 0 | -6 | 1 | 12 | 2 | 0 | 13 | 58 | 10 | 9 | 10 |
| NBA 2022-01-26: MEM 118 at SAS 110 | 25 | 33 | 28 | 24 | 0 | -9 | 6 | -5 | 0 | 0 | 4 | 50 | 16 | 12 | 14 |
| NBA 2022-01-25: SAS 134 at HOU 104 | 34 | 32 | 39 | 29 | 0 | 11 | 4 | 16 | -1 | 0 | 33 | 82 | 18 | 15 | 16 |